Cutaneous malignant melanoma in New Zealand: trends by anatomical site, 1969-1993.

Details

Serval ID
serval:BIB_14293
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cutaneous malignant melanoma in New Zealand: trends by anatomical site, 1969-1993.
Journal
International Journal of Epidemiology
Author(s)
Bulliard J.L., Cox B.
ISSN
0300-5771 (Print)
ISSN-L
0300-5771
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
29
Number
3
Pages
416-423
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
BACKGROUND: Site-specific trend analysis is probably the most effective method available for assessing how the long-term trend in melanoma rates relates to changes in sun exposure and behaviour. New Zealand has very high incidence of and mortality from melanoma and the fraction of melanoma cases and deaths with a site specified has been comparatively high.
METHODS: Trends in incidence and mortality from melanoma in New Zealand were analysed between 1969 and 1993, by sex and body site. A graphical representation of the trend by birth-cohort and age-period-cohort modelling were used.
RESULTS: For all sites combined, the annual increase in incidence was 6.7% (95% CI : 6.3-7.1%) in men and 3.1% (95% CI : 2.3-3.7%) in women. The increase was significantly greater at each site for males. The largest increases occurred for the upper limbs in males (7.3% a year) and the trunk in females (3.8% a year). Incidence rates slowed appreciably in the later years (currently about 26/100 000 for each sex) and no further increase in lifetime risk of melanoma was observed among post World War II generations. Mortality trends paralleled those for incidence with a 25-year gap, with a more modest rate of increase (2-3% per annum for each sex), essentially due to the increased risk among generations born up to 1919 or 1924. Age-standardized death rates have now stabilized in New Zealand at about 5.5/100 000 (men) and 3.2/100 000 (women). Trends between cohorts were the most marked for sites with a likely intermittent pattern of exposure, and were consistent overall for the trunk and the limbs.
CONCLUSIONS: Results support the hypothesis that changes in lifestyle factors resulted in a pattern of carcinogenic exposures that explains both the upsurge in melanoma in the last few decades and the current levelling off in incidence.
Keywords
Adult, Aged, Aged, 80 and over, Cohort Studies, Female, Humans, Incidence, Life Style, Male, Melanoma/mortality, Melanoma/pathology, Middle Aged, Mortality/trends, New Zealand/epidemiology, Risk Assessment, Skin Neoplasms/mortality, Skin Neoplasms/pathology, Sunlight
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 12:06
Last modification date
20/08/2019 12:42
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