Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits
Details
Serval ID
serval:BIB_13F2D0FD73AC
Type
Inproceedings: an article in a conference proceedings.
Collection
Publications
Institution
Title
Multicontrats MRI Improved the Clinico-Radiological Correlation in Early Multiple Sclerosis Patients with Minor Deficits
Title of the conference
22nd annual meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)
Publication state
Published
Issued date
2014
Notes
EPFL-CONF-211188
Abstract
Conventional magnetic resonance imaging (MRI) of
patients with multiple sclerosis provides only limited
insights into the nature of brain tissue damage with
modest clinical-radiological correlations. In this study,
quantitative and semi-quantitative MRI techniques (T1,
T2, T2*, MTR) were applied to study the potential of the
MRI-accessible microstructural information to predict
cognitive and motor scores in patients. A multiparametric
analysis of whole brain abnormalities showed that MRI
measures of microstructural alterations lead to
significant improvement in clinical-radiological
correlations even in the presence of minor functional
deficits.
patients with multiple sclerosis provides only limited
insights into the nature of brain tissue damage with
modest clinical-radiological correlations. In this study,
quantitative and semi-quantitative MRI techniques (T1,
T2, T2*, MTR) were applied to study the potential of the
MRI-accessible microstructural information to predict
cognitive and motor scores in patients. A multiparametric
analysis of whole brain abnormalities showed that MRI
measures of microstructural alterations lead to
significant improvement in clinical-radiological
correlations even in the presence of minor functional
deficits.
Create date
27/11/2015 15:13
Last modification date
21/08/2019 6:36
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