Unusual spread of a penicillin-susceptible methicillin-resistant Staphylococcus aureus clone in a geographic area of low incidence.

Details

Ressource 1Download: serval:BIB_13650.P001 (278.78 [Ko])
State: Public
Version: author
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It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_13650
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Unusual spread of a penicillin-susceptible methicillin-resistant Staphylococcus aureus clone in a geographic area of low incidence.
Journal
Clinical Infectious Diseases
Author(s)
Blanc D.S., Petignat C., Moreillon P., Entenza J.M., Eisenring M., Kleiber H., Wenger A., Troillet N., Blanc C., Francioli P.
ISSN
1058-4838 (Print)
ISSN-L
1058-4838
Publication state
Published
Issued date
1999
Volume
29
Number
6
Pages
1512-1518
Language
english
Abstract
We describe the unusual spread of a penicillin-susceptible methicillin-resistant Staphylococcus aureus (MRSA) clone in hospitals in western Switzerland, where the incidence of MRSA is usually low. During a 2-year period, this clone had been responsible for several outbreaks and had been isolated from >156 persons in 21 institutions. Molecular typing by pulsed-field gel electrophoresis (PFGE) demonstrated that all of these isolates belonged to the same clone. In 1 of the outbreaks, involving 30 cases, the clone was responsible for at least 17 secondary cases. In contrast, during the period of the latter outbreak, 9 other patients harboring different MRSA strains, as assessed by PFGE, were hospitalized in the same wards, but no secondary cases occurred. These observations suggest that this clone, compared with other MRSA strains, had some intrinsic factor(s) that contributed to its ability to disseminate and could thus be considered epidemic.
Keywords
Anti-Bacterial Agents/pharmacology, Cross Infection/microbiology, DNA, Bacterial/analysis, Disease Outbreaks, Electrophoresis, Gel, Pulsed-Field, Geography, Hospitals, University, Humans, Incidence, Methicillin Resistance, Microbial Sensitivity Tests, Penicillins/pharmacology, Staphylococcal Infections/epidemiology, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects, Staphylococcus aureus/genetics, Type="Geographic">Switzerland/epidemiology
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 13:05
Last modification date
25/09/2019 7:08
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