Endometrial Regeneration in Asherman's Syndrome: Clinical and Translational evidence of Stem Cell Therapies.

Details

Serval ID
serval:BIB_1330AD05C35C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Endometrial Regeneration in Asherman's Syndrome: Clinical and Translational evidence of Stem Cell Therapies.
Journal
Current stem cell research & therapy
Author(s)
Hou X., Liu Y., Streuli I., Dällenbach P., Dubuisson J., Ansaldi Y., Pluchino N.
ISSN
2212-3946 (Electronic)
ISSN-L
1574-888X
Publication state
Published
Issued date
2019
Peer-reviewed
Oui
Volume
14
Number
6
Pages
454-459
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Asherman's Syndrome or Intrauterine adhesions is an acquired uterine condition where fibrous scarring forms within the uterine cavity, resulting in reduced menstrual flow, pelvic pain and infertility. Until recently, the molecular mechanisms leading to the formation of fibrosis were poorly understood, and the treatment of Asherman's syndrome has largely focused on hysteroscopic resection of adhesions, hormonal therapy, and physical barriers. Numerous studies have begun exploring the molecular mechanisms behind the fibrotic process underlying Asherman's Syndrome as well as the role of stem cells in the regeneration of the endometrium as a treatment modality. The present review offers a summary of available stem cell-based regeneration studies, as well as highlighting current gaps in research.
Keywords
Endometrium/physiopathology, Female, Gynatresia/physiopathology, Gynatresia/therapy, Humans, Regeneration, Stem Cell Transplantation, Asherman's syndrome, Endometrium, human embryonic stem cells, intrauterine adhesions, scaffold, stem cells.
Pubmed
Web of science
Create date
15/09/2023 12:24
Last modification date
27/09/2023 6:11
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