Nouveaux marqueurs biologiquesde la consommation d’alcool [New biomarkers of alcohol use]

Details

Serval ID
serval:BIB_12A9457B7870
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Nouveaux marqueurs biologiquesde la consommation d’alcool [New biomarkers of alcohol use]
Journal
Revue medicale suisse
Author(s)
Angulo Aguilar A., Bamert L., Sporkert F., Bertholet N.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
05/06/2019
Peer-reviewed
Oui
Volume
15
Number
654
Pages
1173-1176
Language
french
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Estimating alcohol consumption using biomarkers raises interpretation problems. The biomarkers currently used in clinical settings have limited performances to identify unhealthy alcohol use (e.g. CDT, AST, ALT). New direct biomarkers, ethylglucuronide (EtG) and phosphatydilethanol (PEth) are available and offer better sensitivity and specificity compared to indirect biomarkers. In forensic medicine, EtG and PEth are replacing indirect biomarkers. However, in clinical routine practice these markers are usually not considered. Still, for specific purposes such in pre-liver transplant evaluations, direct markers may help specialists in the decision process.
Keywords
Alcohol Drinking, Alcoholism/blood, Biomarkers, Humans, Sensitivity and Specificity
Pubmed
Create date
11/06/2019 11:20
Last modification date
20/08/2019 12:40
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