Cortical regions contributing to the anterior commissure in man.

Details

Serval ID
serval:BIB_12645
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cortical regions contributing to the anterior commissure in man.
Journal
Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation cérébrale
Author(s)
Di Virgilio G., Clarke S., Pizzolato G., Schaffner T.
ISSN
0014-4819
Publication state
Published
Issued date
1999
Peer-reviewed
Oui
Volume
124
Number
1
Pages
1-7
Language
english
Abstract
The human anterior commissure is believed, by extrapolation from data obtained in macaque monkeys, to convey axons from the temporal and orbitofrontal cortex. Reports of interhemispheric transfer and sexual dimorphism related to the anterior commissure, however, make more precise data on the human anterior commissure desirable. We investigated the connectivity of the human anterior commissure in six adults (male and female) that had circumscribed hemispheric lesions in temporal, frontal, parietal or occipital cortices or in infrapallidal white matter using the Nauta for anterogradely degenerating axons. Axons originating in the inferior part of temporal or occipital lobes, occipital convexity and possibly central fissure and prefrontal convexity were found to cross the midsagittal plane in the anterior commissure. The largest contingent of commissural axons originated in the inferior part of the temporal lobe; it displayed a roughly topographic organization, preferentially running through the inferior part of the commissure. The inferior temporal contingent seemed to reach homotopic and heterotopic targets in the opposite hemisphere. Among the latter were the amygdala and possibly the orbitofrontal cortex. The present data suggest that the human anterior commissure conveys axons from much larger territories than expected from work on non-human primates. Similarly to the human and non-human primate corpus callosum, the anterior commissure is roughly topographically organized and participates in heterotopic connectivity.
Keywords
Aged, Aged, 80 and over, Brain Mapping, Cerebral Cortex, Female, Functional Laterality, Humans, Male, Nerve Fibers, Myelinated, Neural Pathways, Occipital Lobe, Prefrontal Cortex, Temporal Lobe
Pubmed
Web of science
Create date
19/11/2007 12:03
Last modification date
20/08/2019 12:40
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