Enrolment of a population-based cohort of newborns at higher risk of developing a chronic condition: the EDEN study.

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State: Public
Version: author
Serval ID
serval:BIB_117
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Enrolment of a population-based cohort of newborns at higher risk of developing a chronic condition: the EDEN study.
Journal
International Journal of Epidemiology
Author(s)
Addor V., Santos-Eggimann B., Fawer C.L., Paccaud F., Calame A.
ISSN
0300-5771
Publication state
Published
Issued date
1997
Peer-reviewed
Oui
Volume
26
Number
2
Pages
340-348
Language
english
Abstract
OBJECTIVE: To describe the methods used at birth to recruit a population-based cohort of newborns of all birthweights at higher risk of having a chronic condition, and to present baseline results. METHODS: Screening of all newborns at hospital discharge for five non-exclusive criteria: (1) low birthweight (LBW), (2) congenital anomalies or genetic disease, (3) specified conditions associated with a high probability of chronicity, (4) referral to a neonatal intensive care unit (NICU), (5) or defined social problems. Calculation of Hobel risk scores for children satisfying > or = 1 criterion. SUBJECTS: All 6477 live births delivered in the 19 maternity hospitals of a geographically defined region (Vaud, Switzerland) to resident mothers in 1993-1994. RESULTS: Twelve per cent (n = 760) of newborns met > or = 1 criterion: 6.3% of all newborns had an LBW (criterion 1), 2.4% had a birth defect, 0.9% met criterion (3), 4.4% stayed in an NICU and 1.6% had serious social problems. Hobel prenatal score was high (> or = 10 points) for 41% of children with > or = 1 criterion, the intrapartum score for 87% and the neonatal score for 68%. CONCLUSIONS: Most newborns identified by the above simple criteria also had elevated perinatal risks. The validity of the criteria will later be tested against the results of the examinations of children with > or = 1 criterion at 18 months and 4 years of age, but the assessment at birth already shows that normal birthweight (NBW) children, in agreement with previous studies, contribute half the children at high risk perinatally.
Keywords
Birth Weight, Chronic Disease/epidemiology, Cohort Studies, Female, Humans, Incidence, Infant, Low Birth Weight, Infant, Newborn, Infant, Newborn, Diseases/epidemiology, Intensive Care Units, Neonatal, Male, Pregnancy, Pregnancy, High-Risk, Registries, Risk Assessment, Switzerland/epidemiology
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 13:02
Last modification date
18/01/2020 8:08
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