Mono- and sesquiterpenes and antifungal constituents from Artemisia species.

Details

Serval ID
serval:BIB_11334
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Mono- and sesquiterpenes and antifungal constituents from Artemisia species.
Journal
Planta Medica
Author(s)
Tan R.X., Lu H., Wolfender J.L., Yu T.T., Zheng W.F., Yang L., Gafner S., Hostettmann K.
ISSN
0032-0943
Publication state
Published
Issued date
1999
Volume
65
Number
1
Pages
64-67
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Abstract
In addition to beta-sitosterol and alpha-amyrin detected in all the investigated species, the extract of the aerial parts of Artemisia giraldii var. giraldii gave stigmasterol, daucosterol, sesamine, luteolin, eupafolin, hispidulin, eupatilin, belamcanidin, pinitol, artemin, ridentin, and a new antifungal monoterpene (named santolinylol) while that of the aerial parts of A. mongolica afforded sesamine, eupafolin, eupatilin, matricarin, and a new germacranolide (3-oxo-11 alpha H-germacra-1(10)E,4Z-dien-12,6 alpha-olide), and that of the aerial parts of A. vestita yielded stigmasterol, daucosterol, umbelliferone, scopolin, scoparone, and isoscopoletin-O-glucoside. Pinitol, first reisolated from Artemisia genus, was shown to inhibit the growth of the human pathogenic fungi Candida albicans, Aspergillus flavus, A. niger, Geotrichun candidum, Trichophyton rubrum, and Epidermophyton floccosum. Umbelliferone was also active against Candida tropicalis, A. flavus, G. candidum, T. rubrum, and E. floccosum. The flavones hispidulin and belamcanidin were almost equally inhibitory to the growth of A. flavus, G. candidum, T. rubrum, and E. floccosum, and santolinylol to C. albicans, A. flavus, A. niger, G. candidum, T. rubrum, and E. floccosum. In addition, ridentin was active against the growth of the plant pathogenic fungus Cladosporium cucumerinum.
Keywords
Antifungal Agents/chemistry, Antifungal Agents/isolation & purification, Artemisia/chemistry, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Molecular Structure, Plants, Medicinal, Sesquiterpenes/chemistry, Sesquiterpenes/isolation & purification
Pubmed
Web of science
Create date
19/11/2007 9:31
Last modification date
20/08/2019 12:38
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