Trachoma: can trichiasis be treated with a sticking-plaster? A randomized clinical trial in China.

Details

Serval ID
serval:BIB_11290
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Trachoma: can trichiasis be treated with a sticking-plaster? A randomized clinical trial in China.
Journal
Tropical Medicine and International Health
Author(s)
Graz B., Xu J.M., Yao Z.S., Han S.R., Kok A.
ISSN
1360-2276[print], 1360-2276[linking]
Publication state
Published
Issued date
1999
Volume
4
Number
3
Pages
222-228
Language
english
Notes
Publication types: Clinical Trial ; Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Trachoma is the most frequent cause of preventable blindness in the world. At the trichiasis/entropion stage, lid surgery is recommended, but many patients only use epilation, which does not prevent loss of vision. We developed a new treatment that should be more accessible than lid surgery and more effective than epilation: a sticking plaster that forces eyelashes back to their correct position. The first randomized controlled trial was conducted in Shanghai with 57 patients to compare the plaster method with epilation. After 3 months of follow-up, with no attrition, 67% of those treated by the new method presented a good clinical status, vs none of those treated by epilation (P < 0.001). The new treatment was well tolerated and lid function remained normal. Although our results show overwhelming benefit of this new, simple treatment for trachoma at the trichiasis stage, more research is needed at the primary health care level and in other settings to determine the potential use of the new method on a large scale and by nonspecialists.
Keywords
Adult, Aged, Bandages, Blindness/prevention &amp, control, China, Cross-Over Studies, Educational Status, Eyelashes, Female, Hair Removal, Humans, Male, Middle Aged, Patient Satisfaction, Trachoma/therapy
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 12:01
Last modification date
20/08/2019 12:38
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