Neuromodulation of the Right Motor Cortex of the Lips With Repetitive Transcranial Magnetic Stimulation to Reduce Phonological Impairment and Improve Naming in Three Persons With Aphasia: A Single-Case Experimental Design.

Details

Serval ID
serval:BIB_104C2CBFAF0C
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Neuromodulation of the Right Motor Cortex of the Lips With Repetitive Transcranial Magnetic Stimulation to Reduce Phonological Impairment and Improve Naming in Three Persons With Aphasia: A Single-Case Experimental Design.
Journal
American journal of speech-language pathology
Author(s)
Arheix-Parras S., Franco J., Siklafidou I.P., Villain M., Rogue C., Python G., Glize B.
ISSN
1558-9110 (Electronic)
ISSN-L
1058-0360
Publication state
Published
Issued date
03/07/2024
Peer-reviewed
Oui
Volume
33
Number
4
Pages
2023-2040
Language
english
Notes
Publication types: Journal Article ; Case Reports
Publication Status: ppublish
Abstract
Repetitive transcranial magnetic stimulation (rTMS) can enhance aphasia recovery. Most studies have used inhibitory stimulation targeting the right inferior frontal gyrus. However, the motor cortex, observed to contribute to the prediction of aphasia recovery, is involved in word production and could be an appropriate target for rTMS. We aimed to observe behavioral changes in a picture naming task induced by inhibitory rTMS targeting the right motor cortex of the lips in people with poststroke aphasia.
Using a single-case experimental design, we included three participants with chronic poststroke aphasia who had phonological deficits. Each participant performed a verbal picture naming task 3 times a week for 2, 3, or 4 weeks (pseudorandom across participants) to establish a baseline naming ability for each participant. These were not therapy sessions, and no feedback was provided. Then, each participant received the intervention, inhibitory continuous theta burst stimulation targeting the right motor cortex of the lips, 3 times a week for 2 weeks. Naming testing continued 3 times a week, for these latter 2 weeks. No therapy was performed at any time during the study.
Visual analysis of the graphs showed a positive effect of rTMS for P2 and P3 on picture naming accuracy and a tendency toward improvement for P1. Statistical analysis showed an improvement after rTMS for P1 (τ = 0.544, p = .013, SE <sub>Tau</sub> = 0.288) and P2 (τ = 0.708, p = .001, SE <sub>Tau</sub> = 0.235). For P3, even if the intervention allowed some improvement, this was statistically nonsignificant due to a learning effect during the baseline naming testing, which lasted the longest, 4 weeks. Regarding specific language features, phonological errors significantly decreased in all patients.
The motor cortex of the lips could be an appropriate target for rTMS to improve naming in people with poststroke aphasia suffering from a phonological deficit. This suggests the possibility to individualize the target for rTMS, according to the patient's linguistic impairment.
Keywords
Humans, Motor Cortex/physiopathology, Transcranial Magnetic Stimulation/methods, Male, Lip/innervation, Middle Aged, Female, Aged, Stroke/complications, Aphasia/etiology, Aphasia/therapy, Treatment Outcome, Phonetics, Articulation Disorders/therapy, Articulation Disorders/etiology, Stroke Rehabilitation/methods
Pubmed
Create date
21/06/2024 10:06
Last modification date
12/07/2024 7:03
Usage data