Benign vs malignant inferolateral early repolarization: Focus on the T wave.

Details

Ressource 1Request a copy Sous embargo indéterminé.
State: Public
Version: author
Serval ID
serval:BIB_102276A5B188
Type
Article: article from journal or magazin.
Collection
Publications
Title
Benign vs malignant inferolateral early repolarization: Focus on the T wave.
Journal
Heart Rhythm : the Official Journal of the Heart Rhythm Society
Author(s)
Roten L., Derval N., Maury P., Mahida S., Pascale P., Leenhardt A., Jesel L., Deisenhofer I., Kautzner J., Probst V., Rollin A., Ruidavets J.B., Ferrières J., Sacher F., Heg D., Scherr D., Komatsu Y., Daly M., Denis A., Shah A., Hocini M., Jaïs P., Haïssaguerre M.
ISSN
1556-3871 (Electronic)
ISSN-L
1547-5271
Publication state
Published
Issued date
2016
Peer-reviewed
Oui
Volume
13
Number
4
Pages
894-902
Language
english
Abstract
BACKGROUND: Inferolateral early repolarization (ER) is highly prevalent and is associated with idiopathic ventricular fibrillation (VF).
OBJECTIVE: The purpose of this study was to evaluate the potential role of T-wave parameters to differentiate between malignant and benign ER.
METHODS: We compared the ECGs of patients with ER and VF (n = 92) with control subjects with asymptomatic ER (n = 247). We assessed J-wave amplitude, QTc interval, T-wave/R-wave (T/R) ratio in leads II and V5, and presence of low-amplitude T waves (T-wave amplitude <0.1 mV and <10% of R-wave amplitude in lead I, II, or V4-V6).
RESULTS: Compared to controls, the VF group had longer QTc intervals (388 ms vs 377 ms, P = .001), higher J-wave amplitudes (0.23 mV vs 0.17 mV, P <.001), higher prevalence of low-amplitude T waves (29% vs 3%, P <.001), and lower T/R ratio (0.18 vs 0.30, P <.001). Logistic regression analysis demonstrated that QTc interval (odds ratio [OR] per 10 ms: 1.15, 95% confidence interval [CI} 1.02-1.30), maximal J-wave amplitude (OR per 0.1 mV: 1.68, 95% CI 1.23-2.31), lower T/R ratio (OR per 0.1 unit: 0.62, 95% CI 0.47-0.81), presence of low-amplitude T waves (OR 3.53, 95% CI 1.26-9.88). and presence of J waves in the inferior leads (OR 2.58, 95% CI 1.18-5.65) were associated with malignant ER.
CONCLUSION: Patients with malignant ER have a higher prevalence of low-amplitude T waves, lower T/R ratio (lead II or V5), and longer QTc interval. The combination of these parameters with J-wave amplitude and distribution of J waves may allow for improved identification of malignant ER.
Pubmed
Create date
10/03/2016 17:01
Last modification date
20/08/2019 13:36
Usage data