Is intra-operative blood flow predictive for early failure of radiocephalic arteriovenous fistula?

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Serval ID
serval:BIB_0F64781E8649
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Is intra-operative blood flow predictive for early failure of radiocephalic arteriovenous fistula?
Journal
Nephrology, Dialysis, Transplantation
Author(s)
Saucy Francois, Haesler Erik, Haller Claude, Deglise Sebastien, Teta Daniel, Corpataux Jean-Marc
ISSN
1460-2385[electronic], 0931-0509[linking]
Publication state
Published
Issued date
2010
Volume
25
Number
3
Pages
862-867
Language
english
Abstract
BACKGROUND: For over 50 years, radiocephalic wrist arteriovenous fistulae (RCAVF) have been the primary and best vascular access for haemodialysis. Nevertheless, early failure due to thrombosis or non-maturation is a major complication resulting in their abandonment. This prospective study was designed to investigate the predictive value of intra-operative blood flow on early failure of primary RCAVF before the first effective dialysis. METHODS: We enrolled patients undergoing creation of primary RCAVF for haemodialysis based on the pre-operative ultrasound vascular mapping discussed in a multidisciplinary approach. Intra-operative blood flow measurement was systematically performed once the anastomosis had been completed using a transit-time ultrasonic flowmeter. During the follow-up, blood flow was estimated by colour flow ultrasound at various intervals. Any events related to the RCAVF were recorded. RESULTS: Autogenous RCAVFs (n = 58) in 58 patients were constructed and followed up for an average of 30 days. Thrombosis and non-maturation occurred in eight (14%) and four (7%) patients, respectively. The intra-operative blood flow in functioning RCAVFs was significantly higher compared to non-functioning RCAVFs (230 vs 98 mL/min; P = 0.007), as well as 1 week (753 vs 228 mL/min; P = 0.0008) and 4 weeks (915 vs 245 mL/min, P < 0.0001) later. Blood flow volume measurements with a cut-off value of 120 mL/min had a sensitivity of 67%, specificity of 75% and positive predictive value of 91%. CONCLUSIONS: Blood flow <120 mL has a good predictive value for early failure in RCAVF. During the procedure, this cut-off value may be used to select appropriately which RCAVF should be investigated in the operation theatre in order to correct in real time any abnormality.
Keywords
Autogenous Fistula, Haemodialysis, Maturation, Thrombosis, Vascular Access Flow, Preoperative Noninvasive Evaluation, Hemodialysis Access Procedures, Vascular Access, Increasing Use, Maturation, Patency, Impact, Artery, Vein, Ultrasonography
Pubmed
Web of science
Open Access
Yes
Create date
16/03/2010 12:59
Last modification date
25/09/2019 6:08
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