A case of insulinoma detected by (68)Ga-DOTANOC PET/CT and missed by (18)F-dihydroxyphenylalanine PET/CT.

Details

Serval ID
serval:BIB_0ECA5FF165FF
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
A case of insulinoma detected by (68)Ga-DOTANOC PET/CT and missed by (18)F-dihydroxyphenylalanine PET/CT.
Journal
Clinical nuclear medicine
Author(s)
Treglia G., Inzani F., Campanini N., Rindi G., Agnes S., Giordano A., Rufini V.
ISSN
1536-0229 (Electronic)
ISSN-L
0363-9762
Publication state
Published
Issued date
06/2013
Peer-reviewed
Oui
Volume
38
Number
6
Pages
e267-70
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
A 65-year-old woman with suspected insulinoma on the basis of clinical, biochemical, and conventional imaging data underwent F-dihydroxyphenylalanine (DOPA) PET/CT and Ga-DOTANOC PET/CT. F-DOPA PET/CT did not show any focal uptake in the pancreas, whereas Ga-DOTANOC PET/CT showed a focal area of intense uptake in the pancreatic tail. The patient underwent surgery and an insulinoma of about 20 mm in diameter was detected in the pancreatic tail. F-DOPA PET may fail in localizing insulin secreting tumors in adults; in these cases, the use of Ga-somatostatin analogs may lead to the correct diagnosis.

Keywords
Aged, Dihydroxyphenylalanine, Female, Fluorine Radioisotopes, Humans, Insulinoma/diagnostic imaging, Insulinoma/pathology, Insulinoma/surgery, Multimodal Imaging, Organometallic Compounds, Radiography, Radionuclide Imaging, Whole Body Imaging
Pubmed
Web of science
Create date
20/08/2017 21:06
Last modification date
20/08/2019 13:35
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