Molecular mechanisms of olfactory detection in insects: beyond receptors.

Details

Serval ID
serval:BIB_0E355E8D256B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Molecular mechanisms of olfactory detection in insects: beyond receptors.
Journal
Open biology
Author(s)
Schmidt H.R., Benton R.
ISSN
2046-2441 (Electronic)
ISSN-L
2046-2441
Publication state
Published
Issued date
10/2020
Peer-reviewed
Oui
Volume
10
Number
10
Pages
200252
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Insects thrive in diverse ecological niches in large part because of their highly sophisticated olfactory systems. Over the last two decades, a major focus in the study of insect olfaction has been on the role of olfactory receptors in mediating neuronal responses to environmental chemicals. In vivo, these receptors operate in specialized structures, called sensilla, which comprise neurons and non-neuronal support cells, extracellular lymph fluid and a precisely shaped cuticle. While sensilla are inherent to odour sensing in insects, we are only just beginning to understand their construction and function. Here, we review recent work that illuminates how odour-evoked neuronal activity is impacted by sensillar morphology, lymph fluid biochemistry, accessory signalling molecules in neurons and the physiological crosstalk between sensillar cells. These advances reveal multi-layered molecular and cellular mechanisms that determine the selectivity, sensitivity and dynamic modulation of odour-evoked responses in insects.
Keywords
Drosophila, neuron, olfaction, physiology, receptor, signalling
Pubmed
Web of science
Open Access
Yes
Create date
14/08/2020 11:38
Last modification date
04/11/2020 6:23
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