No association between grip strength and cardiovascular risk: The CoLaus population-based study.

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State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_0E0099782331
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
No association between grip strength and cardiovascular risk: The CoLaus population-based study.
Journal
International journal of cardiology
Author(s)
Gubelmann C., Vollenweider P., Marques-Vidal P.
ISSN
1874-1754 (Electronic)
ISSN-L
0167-5273
Publication state
Published
Issued date
01/06/2017
Peer-reviewed
Oui
Volume
236
Pages
478-482
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Decreased grip strength (GS) is predictive of cardiovascular (CV) disease but whether it improves CV risk prediction has not been evaluated. We assessed the predictive value of low GS on incident CV events and overall mortality taking into account CV risk equations in a population-based study from Switzerland.
2707 adults (54.8% women, age range 50-75years) were followed for a median time of 5.4years. GS was assessed using a hydraulic hand dynamometer. CV absolute risk at baseline was assessed using recalibrated SCORE, Framingham and PROCAM risk equations. Incident CV events were adjudicated by an independent committee.
160 deaths and 188 incident CV events occurred during follow-up. On bivariate analysis, low GS was associated with increased incident CV events: hazard ratio (HR) and (95% confidence interval) 1.76 (1.13-2.76), p<0.01 but not with overall mortality: HR=1.51 (0.94-2.45), p=0.09. The association between low GS and incident CV events disappeared after adjusting for baseline CV risk: HR=1.23 (0.79-1.94), p=0.36; 1.34 (0.86-2.10), p=0.20 and 1.47 (0.94-2.31), p=0.09 after adjusting for SCORE, Framingham and PROCAM scores, respectively.
Low GS is not predictive of incident CV events when taking into account CV absolute risk.

Keywords
Aged, Cardiovascular Diseases/diagnosis, Cardiovascular Diseases/epidemiology, Cardiovascular Diseases/physiopathology, Female, Follow-Up Studies, Hand Strength/physiology, Humans, Male, Middle Aged, Population Surveillance/methods, Prospective Studies, Risk Factors, Switzerland/epidemiology, Adult, CV events incidence, Cardiovascular risk assessment, Grip strength, Population-based study, Switzerland
Pubmed
Web of science
Open Access
Yes
Create date
07/02/2017 18:30
Last modification date
20/08/2019 12:35
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