Intraocular pressure measurements after corneal collagen crosslinking with riboflavin and ultraviolet A in eyes with keratoconus.
Details
Serval ID
serval:BIB_0D2D8602207B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Intraocular pressure measurements after corneal collagen crosslinking with riboflavin and ultraviolet A in eyes with keratoconus.
Journal
Journal of cataract and refractive surgery
ISSN
1873-4502 (Electronic)
ISSN-L
0886-3350
Publication state
Published
Issued date
10/2010
Peer-reviewed
Oui
Volume
36
Number
10
Pages
1724-1727
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To determine the possible effect of corneal collagen crosslinking (CXL) with riboflavin and ultraviolet A (UVA) on intraocular pressure (IOP) measurements by Goldmann applanation tonometry (GAT).
Institute of Vision and Optics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
Prospective case series.
This noncomparative study measured IOP by GAT before CXL and 6 months and 12 months after CXL.
The study evaluated 55 eyes (55 patients). There was a statistically significant increase in the measured IOP 6 months and 12 months after CXL (both P<.001). The mean measured IOP was 9.95 mm Hg ± 3.01 (SD) before CXL, 11.40 ± 2.89 mm Hg at 6 months, and 11.35 ± 3.38 mm Hg at 12 months. The change in IOP measurements at both postoperative examinations was not correlated with patient age, preoperative pachymetry, or preoperative keratometry readings.
After riboflavin-UVA CXL in eyes with keratoconus, there was a significant increase in IOP measured by GAT that was probably caused by an increase in corneal rigidity.
Institute of Vision and Optics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
Prospective case series.
This noncomparative study measured IOP by GAT before CXL and 6 months and 12 months after CXL.
The study evaluated 55 eyes (55 patients). There was a statistically significant increase in the measured IOP 6 months and 12 months after CXL (both P<.001). The mean measured IOP was 9.95 mm Hg ± 3.01 (SD) before CXL, 11.40 ± 2.89 mm Hg at 6 months, and 11.35 ± 3.38 mm Hg at 12 months. The change in IOP measurements at both postoperative examinations was not correlated with patient age, preoperative pachymetry, or preoperative keratometry readings.
After riboflavin-UVA CXL in eyes with keratoconus, there was a significant increase in IOP measured by GAT that was probably caused by an increase in corneal rigidity.
Keywords
Adolescent, Adult, Collagen/metabolism, Cornea/metabolism, Cross-Linking Reagents, Humans, Intraocular Pressure/physiology, Keratoconus/drug therapy, Keratoconus/metabolism, Photochemotherapy, Photosensitizing Agents/therapeutic use, Prospective Studies, Riboflavin/therapeutic use, Time Factors, Tonometry, Ocular, Ultraviolet Rays, Young Adult
Pubmed
Web of science
Create date
01/10/2019 16:13
Last modification date
06/10/2019 6:26
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