Increased activation in Broca's area after cognitive remediation in schizophrenia.

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State: Public
Version: author
Serval ID
serval:BIB_0BEAB1C073A3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Increased activation in Broca's area after cognitive remediation in schizophrenia.
Journal
Psychiatry Research
Author(s)
Vianin P., Urben S., Magistretti P., Marquet P., Fornari E., Jaugey L.
ISSN
1872-7123 (Electronic)
ISSN-L
0165-1781
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
221
Number
3
Pages
204-209
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
Functional magnetic resonance imaging (fMRI) was used to measure changes in cerebral activity in patients with schizophrenia after participation in the Cognitive Remediation Program for Schizophrenia and other related disorders (RECOS). As RECOS therapists make use of problem-solving and verbal mediation techniques, known to be beneficial in the rehabilitation of dysexecutive syndromes, we expected an increased activation of frontal areas after remediation. Executive functioning and cerebral activation during a covert verbal fluency task were measured in eight patients with schizophrenia before (T1) and after (T2) 14 weeks of RECOS therapy. The same measures were recorded in eight patients with schizophrenia who did not participate in RECOS at the same intervals of time (TAU group). Increased activation in Broca's area, as well as improvements in performance of executive/frontal tasks, was observed after cognitive training. Metacognitive techniques of verbalization are hypothesized to be the main factor underlying the brain changes observed in the present study.
Pubmed
Web of science
Create date
07/03/2014 17:19
Last modification date
12/11/2019 8:08
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