Inhibiteurs de points de contrôle immunitaires et atteinte rénale : mise au point sur une pathologie émergente [Immune checkpoint inhibitors and renal toxicity : update about an emerging pathology]

Details

Serval ID
serval:BIB_09E60B5E42F1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Inhibiteurs de points de contrôle immunitaires et atteinte rénale : mise au point sur une pathologie émergente [Immune checkpoint inhibitors and renal toxicity : update about an emerging pathology]
Journal
Revue medicale suisse
Author(s)
Belkoniene M., Halabi G., Rotman S., Kissling S.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
26/02/2020
Peer-reviewed
Oui
Volume
16
Number
683
Pages
399-403
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Recently, comprehension of immune mechanisms involved in anti-tumor responses has permitted the development of new oncologic drugs called immune checkpoint inhibitors. These drugs act by restoring anti-tumor responses. With their increasing use, we note a rise in the incidence rate of immune related adverse events, which can affect many organs. Renal toxicity, more precisely tubulointerstitial nephritis, is still not well understood but an emerging complication.
Keywords
Humans, Immunologic Factors/adverse effects, Immunologic Factors/therapeutic use, Neoplasms/drug therapy, Neoplasms/immunology, Nephritis, Interstitial/chemically induced
Pubmed
Create date
10/03/2020 17:30
Last modification date
11/06/2020 6:26
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