Prevalence of type 2 diabetes is higher in peripheral artery disease than in coronary artery disease patients.

Details

Serval ID
serval:BIB_090C1F1B09D6
Type
Article: article from journal or magazin.
Collection
Publications
Title
Prevalence of type 2 diabetes is higher in peripheral artery disease than in coronary artery disease patients.
Journal
Diabetes and Vascular Disease Research
Author(s)
Silbernagel G., Rein P., Saely C.H., Engelberger R.P., Willenberg T., Do D.D., Kucher N., Baumgartner I., Drexel H.
ISSN
1752-8984 (Electronic)
ISSN-L
1479-1641
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
12
Number
2
Pages
146-149
Language
english
Abstract
Type 2 diabetes mellitus and pre-diabetes are risk factors for atherosclerosis and are highly prevalent in patients with coronary artery disease. However, the prevalence of impaired glucose metabolism in patients with peripheral artery disease is not as well elucidated. We aimed at comparing prevalence rates of type 2 diabetes mellitus and pre-diabetes, which were diagnosed according to the current American Diabetes Association criteria, among 364 patients with peripheral artery disease, 529 patients with coronary artery disease and 383 controls. The prevalence of type 2 diabetes mellitus in peripheral artery disease patients was 49.7%. It was significantly higher in these patients than in coronary artery disease patients (34.4%; p < 0.001) and controls (21.4%; p < 0.001). Adjusted for sex, age and body mass index, odds ratios for type 2 diabetes mellitus were 2.0 (95% confidence interval 1.5-2.6) comparing the peripheral artery disease group with the coronary artery disease group (p < 0.001) and 4.0 (2.8-5.8) comparing the peripheral artery disease group with controls (p < 0.001). The prevalence of pre-diabetes among non-diabetic subjects was high in all three study groups (64.5% in peripheral artery disease patients, 63.4% in coronary artery disease patients and 61.8% in controls), without significant between-group differences. In conclusion, the prevalence of type 2 diabetes mellitus is even higher in peripheral artery disease patients than in coronary artery disease patients. This observation underlines the need to consider impaired glucose regulation in the management of peripheral artery disease.
Keywords
Aged, Ankle Brachial Index, Austria/epidemiology, Biomarkers/blood, Blood Glucose/analysis, Comorbidity, Coronary Angiography, Coronary Artery Disease/epidemiology, Coronary Artery Disease/radiography, Diabetes Mellitus, Type 2/diagnosis, Diabetes Mellitus, Type 2/epidemiology, Female, Hemoglobin A, Glycosylated/analysis, Humans, Male, Middle Aged, Peripheral Arterial Disease/epidemiology, Peripheral Arterial Disease/ultrasonography, Prevalence, Risk Factors, Switzerland/epidemiology, Ultrasonography, Doppler, Duplex
Pubmed
Web of science
Open Access
Yes
Create date
12/02/2016 11:50
Last modification date
20/08/2019 12:31
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