[ACE inhibitors in the treatment of hypertension in elderly patients]

Details

Serval ID
serval:BIB_08ED41381B52
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
[ACE inhibitors in the treatment of hypertension in elderly patients]
Journal
Schweizerische Rundschau fur Medizin Praxis
Author(s)
Evequoz  D., Reichenstein  T., Waeber  B., Nussberger  J., Brunner  H. R.
ISSN
1013-2058 (Print)
Publication state
Published
Issued date
06/1991
Volume
80
Number
25
Pages
701-6
Notes
English Abstract
Journal Article --- Old month value: Jun 18
Abstract
Recent epidemiological studies clearly indicate that blood pressure rises with age and that hypertension remains a major risk factor for cardiovascular morbidity and mortality in the elderly. An accurate antihypertensive therapy reduces in these patients the incidence of stroke and heart failure. Because of their clinical efficiency and good therapeutic tolerance, the angiotensin-converting enzyme (ACE) inhibitors are first-line drugs for the treatment of elderly hypertensive patients. ACE inhibitions is expected to normalize blood pressure in approximately 40-60% of the patients. When needed, they can be combined with other drugs of different antihypertensive properties. In these cases, the most rational combination therapy consists of an ACE inhibitor with a diuretic or a calcium antagonist.
Keywords
Aged Aging/*physiology Angiotensin-Converting Enzyme Inhibitors/administration & dosage/adverse effects/*therapeutic use Antihypertensive Agents/administration & dosage Cardiovascular Diseases/physiopathology Drug Therapy, Combination Humans Hypertension/*drug therapy/physiopathology Renin-Angiotensin System/drug effects/physiology Risk Factors
Pubmed
Create date
05/03/2008 16:41
Last modification date
20/08/2019 12:31
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