Use of sirolimus-eluting coronary stents in routine clinical practice

Details

Serval ID
serval:BIB_080989568F50
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Use of sirolimus-eluting coronary stents in routine clinical practice
Journal
Catheterization and Cardiovascular Interventions
Author(s)
Goy  J. J., Urban  P., Seydoux  C., De Benedetti  E., Stauffer  J. C.
ISSN
1522-1946 (Print)
Publication state
Published
Issued date
05/2004
Volume
62
Number
1
Pages
26-9; discussion 62
Notes
Evaluation Studies
Journal Article --- Old month value: May
Abstract
Restenosis has long remained the major limitation of intracoronary stenting, but several randomized trials have recently shown that the use of drug-eluting stents appear to reduce markedly the risk of recurrence following treatment of de novo lesions. To evaluate whether the results of randomized trials can be generalized to routine clinical practice, all patients receiving at least one sirolimus-eluting stent (SES) in two Swiss hospitals were entered into a prospective registry. Only target vessels with a reference diameter > 3.5 mm were excluded. Clinical follow-up was obtained after 6 months. A total of 183 patients were included. The procedural success was 97.8% and the incidence of in-hospital MACE was 2.2%. At 7 +/- 2 months, 95.6% of the patients were event-free, and target lesion revascularization was required in only three patients (1.6%). The excellent medium-term results obtained with the SES in randomized trials can be replicated in routine clinical practice.
Keywords
Aged Angioplasty, Transluminal, Percutaneous Coronary Blood Vessel Prosthesis Implantation Coated Materials, Biocompatible/*therapeutic use Coronary Angiography Coronary Disease/radiography/*therapy Coronary Restenosis/etiology/radiography/surgery Disease-Free Survival Female Follow-Up Studies Humans Immunosuppressive Agents/*therapeutic use Male Middle Aged Physician's Practice Patterns Postoperative Complications/etiology/radiography Prospective Studies Reoperation Sirolimus/*therapeutic use *Stents Switzerland Treatment Outcome
Pubmed
Web of science
Create date
28/01/2008 10:11
Last modification date
20/08/2019 12:30
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