Enteric Microbiota⁻Gut⁻Brain Axis from the Perspective of Nuclear Receptors.

Details

Ressource 1Download: ijms-19-02210-v2.pdf (1701.01 [Ko])
State: Public
Version: Final published version
Serval ID
serval:BIB_0796969CC0A5
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Enteric Microbiota⁻Gut⁻Brain Axis from the Perspective of Nuclear Receptors.
Journal
International journal of molecular sciences
Author(s)
Duszka K., Wahli W.
ISSN
1422-0067 (Electronic)
ISSN-L
1422-0067
Publication state
Published
Issued date
28/07/2018
Peer-reviewed
Oui
Volume
19
Number
8
Pages
E2210
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
Nuclear receptors (NRs) play a key role in regulating virtually all body functions, thus maintaining a healthy operating body with all its complex systems. Recently, gut microbiota emerged as major factor contributing to the health of the whole organism. Enteric bacteria have multiple ways to influence their host and several of them involve communication with the brain. Mounting evidence of cooperation between gut flora and NRs is already available. However, the full potential of the microbiota interconnection with NRs remains to be uncovered. Herewith, we present the current state of knowledge on the multifaceted roles of NRs in the enteric microbiota⁻gut⁻brain axis.
Keywords
Animals, Bacteria/metabolism, Bacterial Physiological Phenomena, Brain/physiology, Gastrointestinal Microbiome, Gastrointestinal Tract/microbiology, Gastrointestinal Tract/physiology, Humans, Receptors, Cytoplasmic and Nuclear/metabolism, Signal Transduction, metabolism, microbiota, nuclear receptors, xenobiotics
Pubmed
Web of science
Open Access
Yes
Create date
22/08/2018 9:06
Last modification date
20/08/2019 12:29
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