Wound infection after excision and primary midline closure for pilonidal disease: risk factor analysis to improve patient selection.

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State: Public
Version: author
Serval ID
serval:BIB_077DF42C71AE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Wound infection after excision and primary midline closure for pilonidal disease: risk factor analysis to improve patient selection.
Journal
World Journal of Surgery
Author(s)
Popeskou S., Christoforidis D., Ruffieux C., Demartines N.
ISSN
1432-2323 (Electronic)
ISSN-L
0364-2313
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
35
Number
1
Pages
206-211
Language
english
Notes
Publication types: Journal Article
Abstract
BACKGROUND: Excision and primary midline closure for pilonidal disease (PD) is a simple procedure; however, it is frequently complicated by infection and prolonged healing. The aim of this study was to analyze risk factors for surgical site infection (SSI) in this context.
METHODS: All consecutive patients undergoing excision and primary closure for PD from January 2002 through October 2008 were retrospectively assessed. The end points were SSI, as defined by the Center for Disease Control, and time to healing. Univariable and multivariable risk factor analyses were performed.
RESULTS: One hundred thirty-one patients were included [97 men (74%), median age = 24 (range 15-66) years]. SSI occurred in 41 (31%) patients. Median time to healing was 20 days (range 12-76) in patients without SSI and 62 days (range 20-176) in patients with SSI (P < 0.0001). In univariable and multivariable analyses, smoking [OR = 2.6 (95% CI 1.02, 6.8), P = 0.046] and lack of antibiotic prophylaxis [OR = 5.6 (95% CI 2.5, 14.3), P = 0.001] were significant predictors for SSI. Adjusted for SSI, age over 25 was a significant predictor of prolonged healing.
CONCLUSION: This study suggests that the rate of SSI after excision and primary closure of PD is higher in smokers and could be reduced by antibiotic prophylaxis. SSI significantly prolongs healing time, particularly in patients over 25 years.
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Create date
21/02/2011 10:06
Last modification date
07/10/2019 7:08
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