Prevalence, prophylaxie et traitement de l'encephalopathie de Gayet-Wernicke. Quelle dose et quel mode d'administration de la thiamine? [Prevalence, prophylaxis and treatment of Wernicke encephalopathy. Thiamine, how much and how do we give it?]

Details

Serval ID
serval:BIB_077ABEB7DF32
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Prevalence, prophylaxie et traitement de l'encephalopathie de Gayet-Wernicke. Quelle dose et quel mode d'administration de la thiamine? [Prevalence, prophylaxis and treatment of Wernicke encephalopathy. Thiamine, how much and how do we give it?]
Journal
Revue Médicale Suisse
Author(s)
Meier  S., Daeppen  J. B.
ISSN
1660-9379 (Print)
Publication state
Published
Issued date
06/2005
Volume
1
Number
26
Pages
1740-4
Notes
English Abstract
Journal Article
Review --- Old month value: Jun 29
Abstract
Wernicke's encephalopathy (WE) is an acute neuropsychiatric condition due to thiamine deficiency (vitamin B1) most commonly associated with chronic alcohol abuse. WE is difficult to diagnose because the classical triad of signs (confusion, ataxia and ophthalmoplegia) occurs in only 10% of cases. The presentation is often one of a non-specific confusional state which may easily be attributed to intoxication, alcohol withdrawal or to a concurrent morbidity such as head injury. To improve the outcome, it is important to make a presumptive diagnosis of WE and treat the patients as soon as possible with high-dose parenteral thiamine. Patients with an alcohol problem associated with malnutrition should all be offered a preventive treatment with parenteral thiamine in view of the impaired oral thiamine absorption.
Keywords
Alcoholism/*complications Humans Infusions, Parenteral Prevalence Thiamine/*therapeutic use Wernicke Encephalopathy/*drug therapy/epidemiology/etiology
Pubmed
Create date
25/01/2008 17:13
Last modification date
20/08/2019 12:29
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