Cohort profile: Antiretroviral Therapy Cohort Collaboration (ART-CC).

Details

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It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_074B0C696B48
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cohort profile: Antiretroviral Therapy Cohort Collaboration (ART-CC).
Journal
International Journal of Epidemiology
Author(s)
May M.T., Ingle S.M., Costagliola D., Justice A.C., de Wolf F., Cavassini M., D'Arminio Monforte A., Casabona J., Hogg R.S., Mocroft A., Lampe F.C., Dabis F., Fätkenheuer G., Sterling T.R., del Amo J., Gill M.J., Crane H.M., Saag M.S., Guest J., Brodt H.R., Sterne J.A.
Working group(s)
Antiretroviral Cohort Collaboration
Contributor(s)
Boulle A., Brodt HR., Casabona J., Cavassini M., Chêne G., Costagliola D., Dabis F., D'Arminio Monforte A., del Amo J., de Wolf F., Fätkenheuer G., Gill J., Guest J., Hans-Ulrich Haerry D., Hogg R., Justice A., Mocroft A., Kitahata M., Lampe F., Reiss P., Saag M., Sterling T., Williams M., Zangerle R., Sterne J., May M., Ingle S.
ISSN
1464-3685 (Electronic)
ISSN-L
0300-5771
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
43
Number
3
Pages
691-702
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.Publication Status: ppublish
licence nationale
Abstract
The advent of effective combination antiretroviral therapy (ART) in 1996 resulted in fewer patients experiencing clinical events, so that some prognostic analyses of individual cohort studies of human immunodeficiency virus-infected individuals had low statistical power. Because of this, the Antiretroviral Therapy Cohort Collaboration (ART-CC) of HIV cohort studies in Europe and North America was established in 2000, with the aim of studying the prognosis for clinical events in acquired immune deficiency syndrome (AIDS) and the mortality of adult patients treated for HIV-1 infection. In 2002, the ART-CC collected data on more than 12,000 patients in 13 cohorts who had begun combination ART between 1995 and 2001. Subsequent updates took place in 2004, 2006, 2008, and 2010. The ART-CC data base now includes data on more than 70,000 patients participating in 19 cohorts who began treatment before the end of 2009. Data are collected on patient demographics (e.g. sex, age, assumed transmission group, race/ethnicity, geographical origin), HIV biomarkers (e.g. CD4 cell count, plasma viral load of HIV-1), ART regimen, dates and types of AIDS events, and dates and causes of death. In recent years, additional data on co-infections such as hepatitis C; risk factors such as smoking, alcohol and drug use; non-HIV biomarkers such as haemoglobin and liver enzymes; and adherence to ART have been collected whenever available. The data remain the property of the contributing cohorts, whose representatives manage the ART-CC via the steering committee of the Collaboration. External collaboration is welcomed. Details of contacts are given on the ART-CC website (www.art-cohort-collaboration.org).
Pubmed
Web of science
Open Access
Yes
Create date
05/08/2014 18:56
Last modification date
01/10/2019 7:16
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