Anti-inflammatory effect of diclofenac drops after argon laser trabeculoplasty

Details

Serval ID
serval:BIB_06EB26C12884
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Anti-inflammatory effect of diclofenac drops after argon laser trabeculoplasty
Journal
Archives of Ophthalmology
Author(s)
Herbort  C. P., Mermoud  A., Schnyder  C., Pittet  N.
ISSN
0003-9950 (Print)
Publication state
Published
Issued date
04/1993
Volume
111
Number
4
Pages
481-3
Notes
Clinical Trial
Journal Article
Randomized Controlled Trial --- Old month value: Apr
Abstract
Using a laser flare-cell meter, the anti-inflammatory effect of diclofenac sodium drops was evaluated after argon laser trabeculoplasty in a double-masked placebo-controlled study. Fifty-three eyes with pseudoexfoliative (43 eyes) or pigmentary glaucoma (10 eyes) were randomly assigned to treatment (n = 27) or placebo (n = 26) groups. Diclofenac (0.1%) or placebo drops were administered once before and after trabeculoplasty and then four times daily for a total of 4 days. Visual acuity, intraocular pressure, and anterior chamber flare, measured with the laser flare-cell meter, were evaluated before trabeculoplasty, 3 and 6 hours after trabeculoplasty, and 1, 2, 4, 7, and 14 days after trabeculoplasty. Flare increase after argon laser trabeculoplasty was completely blocked by 0.1% topical diclofenac and the mean of maximal flare increases was reduced significantly in the diclofenac group. Therefore, 0.1% diclofenac drops represent a very efficient anti-inflammatory therapy after argon laser trabeculoplasty.
Keywords
Aged Anterior Eye Segment/*surgery Diclofenac/administration & dosage/*therapeutic use Double-Blind Method Drug Administration Schedule Endophthalmitis/etiology/*prevention & control Eye Diseases/diagnosis Female Glaucoma, Open-Angle/physiopathology/*surgery Humans Intraocular Pressure Laser Surgery/*adverse effects Male Ophthalmic Solutions/therapeutic use Premedication Prospective Studies Trabeculectomy/*adverse effects Visual Acuity
Pubmed
Web of science
Create date
28/01/2008 12:50
Last modification date
20/08/2019 12:29
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