Phylogeography, more than elevation, accounts for sexchromosome differentiation in Swiss populations of the common frog (Rana temporaria)

Details

Serval ID
serval:BIB_06E58546A791
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Phylogeography, more than elevation, accounts for sexchromosome differentiation in Swiss populations of the common frog (Rana temporaria)
Journal
Evolution
Author(s)
Phillips B C, Rodrigues N, Jansen van Rensburg A, Perrin N
ISSN
0014-3820
Publication state
Published
Issued date
03/03/2020
Peer-reviewed
Oui
Volume
74
Number
3
Pages
644-654
Language
english
Abstract
Sex chromosomes in vertebrates range from highly heteromorphic (as in most birds and mammals) to strictly homomorphic (as in many fishes, amphibians, and non-avian reptiles). Reasons for these contrasted evolutionary trajectories remain unclear, but species such as common frogs with polymorphism in the extent of sex-chromosome differentiation may potentially deliver important clues. By investigating 92 common-frog populations from a wide range of elevations throughout Switzerland, we show that sex-chromosome differentiation strongly correlates with alleles at the candidate sex-determining gene Dmrt1. Y-specific Dmrt1 haplotypes cluster into two main haplogroups, YA and YB, with a phylogeographic signal that parallels mtDNA haplotypes: YA populations, with mostly well-differentiated sex chromosomes, occur primarily south of the main alpine ridge that bisects Switzerland, while YB populations, with mostly undifferentiated (proto-)sex chromosomes, occur north of this ridge. Elevation has only a marginal effect, opposing previous suggestions of a major role for climate on sex-chromosome differentiation. The Y-haplotype effect might result from differences in the penetrance of alleles at the sex-determining locus (such that sex reversal and ensuing X-Y recombination are more frequent in YB populations), and/or fixation of an inversion on YA (as supported by the empirical observation that YA haplotypes might not recombine in XYA females).
Keywords
Amphibians, Dmrt1, sex determination, sex races, sex reversal, X-Y recombination
Funding(s)
Swiss National Science Foundation / Projects / 31003A_166323
Create date
04/10/2019 15:57
Last modification date
04/03/2020 6:19
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