Phylogeography, more than elevation, accounts for sexchromosome differentiation in Swiss populations of the common frog (Rana temporaria)

Details

Serval ID
serval:BIB_06E58546A791
Type
Article: article from journal or magazin.
Collection
Publications
Title
Phylogeography, more than elevation, accounts for sexchromosome differentiation in Swiss populations of the common frog (Rana temporaria)
Journal
Evolution
Author(s)
Phillips B C, Rodrigues N, Jansen van Rensburg A, Perrin N
ISSN
0014-3820
Publication state
In Press
Language
english
Abstract
Sex chromosomes in vertebrates range from highly heteromorphic (as in most birds and mammals) to strictly homomorphic (as in many fishes, amphibians, and non-avian reptiles). Reasons for these contrasted evolutionary trajectories remain unclear, but species such as common frogs with polymorphism in the extent of sex-chromosome differentiation may potentially deliver important clues. By investigating 92 common-frog populations from a wide range of elevations throughout Switzerland, we show that sex-chromosome differentiation strongly correlates with alleles at the candidate sex-determining gene Dmrt1. Y-specific Dmrt1 haplotypes cluster into two main haplogroups, YA and YB, with a phylogeographic signal that parallels mtDNA haplotypes: YA populations, with mostly well-differentiated sex chromosomes, occur primarily south of the main alpine ridge that bisects Switzerland, while YB populations, with mostly undifferentiated (proto-)sex chromosomes, occur north of this ridge. Elevation has only a marginal effect, opposing previous suggestions of a major role for climate on sex-chromosome differentiation. The Y-haplotype effect might result from differences in the penetrance of alleles at the sex-determining locus (such that sex reversal and ensuing X-Y recombination are more frequent in YB populations), and/or fixation of an inversion on YA (as supported by the empirical observation that YA haplotypes might not recombine in XYA females).
Keywords
Amphibians, Dmrt1, sex determination, sex races, sex reversal, X-Y recombination
Funding(s)
Swiss National Science Foundation / Projects / 31003A_166323
Create date
04/10/2019 15:57
Last modification date
03/12/2019 6:23
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