The Effect of LASIK Procedure on Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness in Myopic Eyes.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_057FA33FBC4D
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
The Effect of LASIK Procedure on Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness in Myopic Eyes.
Journal
BioMed research international
Author(s)
Zivkovic M., Jaksic V., Giarmoukakis A., Grentzelos M., Zlatanovic M., Zlatanovic G., Miljkovic A., Jovanovic S., Stamenkovic M., Kymionis G.
ISSN
2314-6141 (Electronic)
Publication state
Published
Issued date
2017
Peer-reviewed
Oui
Volume
2017
Pages
8923819
Language
english
Notes
Publication types: Journal Article ; Observational Study
Publication Status: ppublish
Abstract
To evaluate the effect of applied suction during microkeratome-assisted laser in situ keratomileusis (LASIK) procedure on peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular ganglion cell-inner plexiform layer (GC-IPL) thickness.
89 patients (124 eyes) with established myopia range from -3.0 to -8.0 diopters and no associated ocular diseases were included in this study. RNFL and GC-IPL thickness measurements were performed by spectral domain optical coherence tomography (SD OCT) one day before LASIK and at 1 and 6 months postoperatively.
Mean RNFL thickness prior to LASIK was 93.86 ± 12.17 <i>μ</i> m while the first month and the sixth month postoperatively were 94.01 ± 12.04 <i>μ</i> m and 94.46 ± 12.27 <i>μ</i> m, respectively. Comparing results, there is no significant difference between baseline, one month, and six months postoperatively for mean RNFL ( <i>p</i> > 0.05). Mean GC-IPL thickness was 81.70 ± 7.47 <i>μ</i> m preoperatively with no significant difference during the follow-up period (82.03 ± 7.69 <i>μ</i> m versus 81.84 ± 7.64 <i>μ</i> m; <i>p</i> > 0.05).
RNFL and GC-IPL complex thickness remained unaffected following LASIK intervention.
Keywords
Adolescent, Adult, Female, Humans, Keratomileusis, Laser In Situ/methods, Male, Middle Aged, Myopia/pathology, Myopia/surgery, Nerve Fibers/physiology, Postoperative Period, Prospective Studies, Retina/pathology, Retina/surgery, Retinal Ganglion Cells/physiology, Tomography, Optical Coherence/methods, Young Adult
Pubmed
Web of science
Open Access
Yes
Create date
19/01/2018 9:53
Last modification date
13/01/2021 7:08
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