Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes.

Details

Serval ID
serval:BIB_04F30F5C7877
Type
Article: article from journal or magazin.
Collection
Publications
Title
Nonlinkage of major histocompatibility complex class I and class II loci in bony fishes.
Journal
Immunogenetics
Author(s)
Sato A., Figueroa F., Murray B.W., Málaga-Trillo E., Zaleska-Rutczynska Z., Sültmann H., Toyosawa S., Wedekind C., Steck N., Klein J.
ISSN
0093-7711 (Print)
ISSN-L
0093-7711
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
51
Number
2
Pages
108-116
Language
english
Abstract
In tetrapods, the functional (classical) class I and class II B loci of the major histocompatibility complex (Mhc) are tightly linked in a single chromosomal region. In an earlier study, we demonstrated that in the zebrafish, Danio rerio, order Cypriniformes, the two classes are present on different chromosomes. Here, we show that the situation is similar in the stickleback, Gasterosteus aculeatus, order Gasterosteiformes, the common guppy, Poecilia reticulata, order Cyprinodontiformes, and the cichlid fish Oreochromis niloticus, order Perciformes. These data, together with unpublished results from other laboratories suggest that in all Euteleostei, the classical class I and class II B loci are in separate linkage groups, and that in at least some of these taxa, the class II loci are in two different groups. Since Euteleostei are at least as numerous as tetrapods, in approximately one-half of jawed vertebrates, the class I and class II regions are not linked.
Keywords
Animals, Embryo, Nonmammalian, Female, Fishes/embryology, Fishes/genetics, Genes, MHC Class I/genetics, Genes, MHC Class II/genetics, Genetic Linkage, Haploidy, Male, Perches/embryology, Perches/genetics, Phylogeny, Poecilia/embryology, Poecilia/genetics, Species Specificity
Pubmed
Web of science
Create date
25/01/2008 11:43
Last modification date
20/08/2019 13:26
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