Validation of the IMPACT-III quality of life questionnaire in Swiss children with inflammatory bowel disease.

Details

Serval ID
serval:BIB_03FFD00B969B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Validation of the IMPACT-III quality of life questionnaire in Swiss children with inflammatory bowel disease.
Journal
Journal of Crohn's and Colitis
Author(s)
Werner H., Landolt M.A., Buehr P., Koller R., Nydegger A., Spalinger J., Heyland K., Schibli S., Braegger C.P.
Working group(s)
Swiss IBD Cohort Study Group
ISSN
1876-4479 (Electronic)
ISSN-L
1873-9946
Publication state
Published
Issued date
2014
Volume
8
Number
7
Pages
641-648
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) frequently manifests during childhood and adolescence. For providing and understanding a comprehensive picture of a patients' health status, health-related quality of life (HRQoL) instruments are an essential complement to clinical symptoms and functional limitations. Currently, the IMPACT-III questionnaire is one of the most frequently used disease-specific HRQoL instrument among patients with IBD. However, there is a lack of studies examining the validation and reliability of this instrument.
METHODS: 146 paediatric IBD patients from the multicenter Swiss IBD paediatric cohort study database were included in the study. Medical and laboratory data were extracted from the hospital records. HRQoL data were assessed by means of standardized questionnaires filled out by the patients in a face-to-face interview.
RESULTS: The original six IMPACT-III domain scales could not be replicated in the current sample. A principal component analysis with the extraction of four factor scores revealed the most robust solution. The four factors indicated good internal reliability (Cronbach's alpha=.64-.86), good concurrent validity measured by correlations with the generic KIDSCREEN-27 scales and excellent discriminant validity for the dimension of physical functioning measured by HRQoL differences for active and inactive severity groups (p<.001, d=1.04).
CONCLUSIONS: This study with Swiss children with IBD indicates good validity and reliability for the IMPACT-III questionnaire. However, our findings suggest a slightly different factor structure than originally proposed. The IMPACT-III questionnaire can be recommended for its use in clinical practice. The factor structure should be further examined in other samples.
Pubmed
Web of science
Open Access
Yes
Create date
07/02/2014 15:06
Last modification date
20/08/2019 12:25
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