Ambulatory blood pressure measurement and antihypertensive therapy.

Details

Serval ID
serval:BIB_03C91228DAFE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Ambulatory blood pressure measurement and antihypertensive therapy.
Journal
Journal of hypertension. Supplement
Author(s)
Waeber B., Burnier M., Perret F., Nussberger J., Brunner H.R.
ISSN
0952-1178
Publication state
Published
Issued date
1989
Volume
7
Number
3
Pages
S33-39
Language
english
Abstract
The traditional basis for assessing the effect of antihypertensive therapy is the blood pressure reading taken by a physician. However, several recent trials have been designed to evaluate the blood pressure lowering effect of various therapeutic agents during the patients' normal daytime activities, using a portable, semi-automatic blood pressure recorder. The results have shown that in a given patient, blood pressure measured at the physician's office often differs greatly from that prevailing during the rest of the day. This is true both in treated and untreated hypertensive patients. The difference between office and ambulatory recorded pressures cannot be predicted from blood pressure levels measured by the physician. Therefore, a prospective study was carried out in patients with diastolic blood pressures that were uncontrolled at the physician's office despite antihypertensive therapy. The purpose was to evaluate the response of recorded ambulatory blood pressure to treatment adjustments aimed at reducing office blood pressure below a pre-set target level. Only patients with high ambulatory blood pressures at the outset appeared to benefit from further changes in therapy. Thus, ambulatory blood pressure monitoring can be used to identify those patients who remain hypertensive only when facing the physician, despite antihypertensive therapy. Ambulatory monitoring could thus help to evaluate the efficacy of antihypertensive therapy and allow individual treatment.
Keywords
Antihypertensive Agents, Blood Pressure, Blood Pressure Determination, Circadian Rhythm, Clinical Trials as Topic, Humans, Hypertension, Monitoring, Physiologic, Placebos, Prospective Studies, Stress, Psychological
Pubmed
Web of science
Create date
25/01/2008 12:56
Last modification date
20/08/2019 12:25
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