Molecular electron microscopy: state of the art and current challenges.

Details

Serval ID
serval:BIB_03804BFAF887
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Molecular electron microscopy: state of the art and current challenges.
Journal
ACS chemical biology
Author(s)
Stahlberg H., Walz T.
ISSN
1554-8937 (Electronic)
ISSN-L
1554-8929
Publication state
Published
Issued date
16/05/2008
Peer-reviewed
Oui
Volume
3
Number
5
Pages
268-281
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
Publication Status: ppublish
Abstract
The objective of molecular electron microscopy (EM) is to use electron microscopes to visualize the structure of biological molecules. This Review provides a brief overview of the methods used in molecular EM, their respective strengths and successes, and current developments that promise an even more exciting future for molecular EM in the structural investigation of proteins and macromolecular complexes, studied in isolation or in the context of cells and tissues.
Keywords
Crystallography, Microscopy, Electron/methods, Proteins/chemistry, Proteins/ultrastructure, Sensitivity and Specificity
Pubmed
Web of science
Open Access
Yes
Create date
09/06/2023 16:03
Last modification date
28/07/2023 6:58
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