Sleep disorders in boys with Duchenne muscular dystrophy.

Details

Serval ID
serval:BIB_030252ECA216
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Sleep disorders in boys with Duchenne muscular dystrophy.
Journal
Acta Paediatrica
Author(s)
Bloetzer C., Jeannet P.Y., Lynch B., Newman C.J.
ISSN
1651-2227 (Electronic)
ISSN-L
0803-5253
Publication state
Published
Issued date
2012
Volume
101
Number
12
Pages
1265-1269
Language
english
Notes
Publication types: Journal Article
Abstract
Aim:  Determine the frequency and predictors of sleep disorders in boys with Duchenne Muscular Dystrophy (DMD). Method:  Cross-sectional study by postal questionnaire. Sleep disturbances were assessed using the Sleep Disturbance Scale for Children (validated on 1157 healthy children). A total sleep score and six sleep disturbance factors representing the most common sleep disorders were computed. Potential associations between pathological scores and personal, medical and environmental factors were assessed. Results:  Sixteen of 63 boys (25.4%) had a pathological total sleep score compared with 3% in the general population. The most prevalent sleep disorders were disorders of initiating and maintaining sleep (DIMS) 29.7%, sleep-related breathing disorders 15.6% and sleep hyperhydrosis 14.3%. On multivariate analysis, pathological total sleep scores were associated with the need to be moved by a carer (OR = 9.4; 95%CI: 2.2-40.7; p = 0.003) and being the child of a single-parent family (OR = 7.2; 95%CI: 1.5-35.1; p = 0.015) and DIMS with the need to be moved by a carer (OR = 18.0; 95%CI: 2.9-110.6; p = 0.002), steroid treatment (OR = 7.7; 95%CI: 1.4-44.0; p = 0.021) and being the child of a single-parent family (OR = 7.0; 95%CI: 1.3-38.4; p = 0.025). Conclusion:  Sleep disturbances are frequent in boys with DMD and are strongly associated with immobility. Sleep should be systematically assessed in DMD to implement appropriate interventions.
Pubmed
Web of science
Open Access
Yes
Create date
19/12/2012 11:13
Last modification date
20/08/2019 12:25
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