Scientific Advances in Lung Cancer 2015.

Details

Serval ID
serval:BIB_02E8A7A685FB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Scientific Advances in Lung Cancer 2015.
Journal
Journal of thoracic oncology
Author(s)
Tsao A.S., Scagliotti G.V., Bunn P.A., Carbone D.P., Warren G.W., Bai C., de Koning H.J., Yousaf-Khan A.U., McWilliams A., Tsao M.S., Adusumilli P.S., Rami-Porta R., Asamura H., Van Schil P.E., Darling G.E., Ramalingam S.S., Gomez D.R., Rosenzweig K.E., Zimmermann S., Peters S., Ignatius Ou S.H., Reungwetwattana T., Jänne P.A., Mok T.S., Wakelee H.A., Pirker R., Mazières J., Brahmer J.R., Zhou Y., Herbst R.S., Papadimitrakopoulou V.A., Redman M.W., Wynes M.W., Gandara D.R., Kelly R.J., Hirsch F.R., Pass H.I.
ISSN
1556-1380 (Electronic)
ISSN-L
1556-0864
Publication state
Published
Issued date
05/2016
Peer-reviewed
Oui
Volume
11
Number
5
Pages
613-638
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.

Keywords
Humans, Immunotherapy, Lung Neoplasms/diagnosis, Lung Neoplasms/therapy, Precision Medicine, Quality of Life, Adjuvant chemotherapy, Biomarkers, Cancer prevention, Gene mutations, Lung cancer, Master protocols, Pathology, Radiotherapy, Screening, Smoking cessation, Staging, Surgery, Targeted therapy, Value of therapy
Pubmed
Web of science
Open Access
Yes
Create date
10/04/2016 13:22
Last modification date
02/09/2019 17:03
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