F18-choline/C11-choline PET/CT thyroid incidentalomas.

Details

Serval ID
serval:BIB_02AFDD3D0077
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
F18-choline/C11-choline PET/CT thyroid incidentalomas.
Journal
Endocrine
Author(s)
Bertagna F., Albano D., Giovanella L., Giubbini R., Treglia G.
ISSN
1559-0100 (Electronic)
ISSN-L
1355-008X
Publication state
Published
Issued date
05/2019
Peer-reviewed
Oui
Volume
64
Number
2
Pages
203-208
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Thyroid incidentaloma is defined as a thyroid lesion incidentally and newly detected by imaging techniques performed for an unrelated purpose and especially for a non-thyroid disease. Aim of this review is to evaluate the prevalence and clinical significance of focal incidental radiolabelled choline uptake in the thyroid gland (CTI) revealed by PET or PET/CT.
A comprehensive computer literature search of the PubMed/MEDLINE, Scopus, and Embase databases was conducted to find relevant published articles about the prevalence and clinical significance of CTIs detected by PET or PET/CT in patients studied for other oncologic purposes.
Fifteen articles (14 case reports, one retrospective study on a larger population sample) were included in the systematic review. Considering the case reports, 7/14 CTIs were benign and 7/14 malignant. In the retrospective study on a larger population sample, 14/15 CTIs which underwent further investigations were benign.
Despite very rare but probably underestimated, CTIs frequently signal in the presence of unexpected lesions in the thyroid that differ from the indicated reason for which the patient was initially scanned, and the risk of malignancy is not negligible.
Keywords
Fluorodeoxyglucose F18, Humans, Incidental Findings, Positron Emission Tomography Computed Tomography, Thyroid Gland/diagnostic imaging, Thyroid Neoplasms/diagnostic imaging, Choline, Incidental, PET/CT, Positron emission tomography, Thyroid, Thyroid incidentaloma
Pubmed
Web of science
Create date
08/02/2019 17:31
Last modification date
26/06/2020 5:21
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