Impact of Mediterranean Diet on Lipid Composition in the Colaus-PsyColaus Study.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_02A3EB85F780
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Impact of Mediterranean Diet on Lipid Composition in the Colaus-PsyColaus Study.
Journal
Nutrients
Author(s)
Flatscher M., Garnier A., Marques-Vidal P., Kraege V.
ISSN
2072-6643 (Electronic)
ISSN-L
2072-6643
Publication state
Published
Issued date
03/11/2023
Peer-reviewed
Oui
Volume
15
Number
21
Pages
4659
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
High adherence to the Mediterranean diet (MD) has been associated with lower incidence of cardiovascular disease, increased HDL-cholesterol levels, and decreased triglycerides (TG), and total and LDL cholesterol levels. We aimed to assess the association of MD adherence at baseline with the lipid profile both cross-sectionally and prospectively in a sample of apparently healthy community-dwelling subjects. We conducted three cross-sectional studies using data from follow-ups 1 (FU1, 2009-2012), 2 (FU2, 2014-2017), and 3 (FU3, 2018-2021) of CoLaus|PsyCoLaus, a population-based sample from Lausanne, Switzerland. Dietary intake was assessed with a food frequency questionnaire. Two MD scores (Trichopoulou and Vormund) were computed, ranging from 0 (low) to 9 (high). In total, LDL and HDL cholesterol and TG were assessed. Incident dyslipidemia was defined as hypolipidemic treatment at FU2 or FU3. Overall, 4249 participants from FU1 (53.7% women, 57.6 ± 10.5 years, Trichopoulou 4.0 ± 1.5, Vormund 4.7 ± 1.9) were included. Neither MD score correlated significantly with the lipid markers and similar results were obtained according to the hypolipidemic status. Among the 3092 untreated FU1 participants with FU2 and FU3 data, 349 (11.3%) developed dyslipidemia by FU2 or FU3. No difference in MD scores was found between participants who developed dyslipidemia and those who did not (4.1 ± 1.5 vs. 4.0 ± 1.5 and 4.8 ± 1.8 vs. 4.8 ± 1.9 for Trichopoulou and Vormund, respectively, p > 0.05). Finally, no associations were found between MD score and lipid changes at 5 or 10 years. Contrary to other studies, adherence to MD at baseline did not show any significant effects on lipid composition/incident dyslipidemia in Colaus|PsyCoLaus participants.
Keywords
Humans, Female, Male, Diet, Mediterranean, Cross-Sectional Studies, Triglycerides, Cholesterol, HDL, Dyslipidemias/epidemiology, Dyslipidemias/prevention & control, diet score, dyslipidemia, lipids, mediterranean diet, non communicable diseases, nutrition
Pubmed
Web of science
Open Access
Yes
Create date
03/11/2023 17:33
Last modification date
27/05/2024 7:18
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