Replication of hepatitis C virus

Details

Serval ID
serval:BIB_028003E82846
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Replication of hepatitis C virus
Journal
Nature Reviews Microbiology
Author(s)
Moradpour D., Penin F., Rice C. M.
ISSN
1740-1534 (Electronic)
Publication state
Published
Issued date
06/2007
Volume
5
Number
6
Pages
453-63
Notes
Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review --- Old month value: Jun
Abstract
Exciting progress has recently been made in understanding the replication of hepatitis C virus, a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma worldwide. The development of complete cell-culture systems should now enable the systematic dissection of the entire viral lifecycle, providing insights into the hitherto difficult-to-study early and late steps. These efforts have already translated into the identification of novel antiviral targets and the development of new therapeutic strategies, some of which are currently undergoing clinical evaluation.
Keywords
Hepacivirus/genetics/*physiology Hepatitis C/virology Humans Viral Proteins/chemistry/physiology Virus Cultivation/methods Virus Internalization *Virus Replication
Pubmed
Web of science
Create date
25/01/2008 16:06
Last modification date
20/08/2019 12:24
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