Phénylcétonurie maternelle [Maternal phenylketonuria]

Details

Serval ID
serval:BIB_006B54CFB657
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Phénylcétonurie maternelle [Maternal phenylketonuria]
Journal
Revue medicale de la Suisse romande
Author(s)
Matthieu J.M., Boulat O., Bianchi N.
ISSN
0035-3655 (Print)
ISSN-L
0035-3655
Publication state
Published
Issued date
04/2001
Peer-reviewed
Oui
Volume
121
Number
4
Pages
297-300
Language
french
Notes
Publication types: Case Reports ; English Abstract ; Journal Article
Publication Status: ppublish
Abstract
The child of a phenylketonuric woman is exposed during pregnancy to a high risk of growth retardation and malformation. The frequency of these abnormalities is proportional to the maternal phenylalanine blood concentrations. If a strict low protein diet is followed before conception and throughout gestation the risks of abnormalities are not higher than in the normal population. The maternal blood phenylalanine levels must be maintained between 120 and 250 mumol/l and the tyrosine blood levels between 45 and 90 mumol/l. Weekly blood analyses are mandatory. Regular dietary controls are necessary to assure that the adequate energetic intake and the correct amounts of vitamins and minerals recommended for a pregnant woman are sustained. A case report is the opportunity to discuss certain practical aspects concerning the monitoring of the pregnancy of a phenylketonuric woman and to make general recommendations.
Keywords
Adult, Congenital Abnormalities/etiology, Diet, Protein-Restricted, Energy Intake, Female, Fetal Growth Retardation/etiology, Gestational Age, Humans, Nutritional Requirements, Phenylalanine/blood, Phenylketonuria, Maternal/blood, Phenylketonuria, Maternal/complications, Phenylketonuria, Maternal/diagnosis, Phenylketonuria, Maternal/diet therapy, Pregnancy, Prenatal Care/methods, Risk Factors, Tyrosine/blood
Pubmed
Create date
05/02/2008 11:24
Last modification date
20/07/2024 7:05
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